Chemistry of Oxymorphone HCL
The chemical formula of Oxymorphone HCL is “4, 5α -epoxy-3, 14-dihydroxy-17-methylmorphinan-6-one hydrochloride”. The purity of this substance in its purest forms has been calculated to be approximately equal to or greater than 99.8% while the total impurities in most cases in less than or equal to 0.2%.
The recommended storage temperature for the drugs is either room temperature or between 20oC to 25oC. In order to keep the drug preserved for a long period of time, it is advised to keep the drug at a low temperature of – 20oC while the stability of the molecule of this drug is known to be equal to or greater than two to three years. The chemical formulas of Hydromorphone HCL is C17H20ClNO4. The Oxymorphone HCL is partly soluble in ether and alcohol but freely soluble in water. Its molecular weight is 337.80.
Tablets and Dosage of Oxymorphone HCL
Each Oxymorphone HCL tablet contains the inactive ingredients below: polyethylene oxide, glycol, α-tocopherol, marcogol, hypromellose, polyethylene citric acid, polyvinyl alcohol, titanium dioxide, and talc. In addition to this
5 mg, 7.5 mg, and 30 mg tablets contain iron oxide red
5 mg tablets contain iron oxide yellow and iron oxide black
10 mg tablets contain FD&C yellow No. 6
20 mg tablets contain FD&C blue No. 1, FD&C yellow No. 6, and D&C yellow No. 10
40 mg tablets contain FD&C yellow No. 6, and D&C yellow No. 10
Effects of Oxymorphone HCL
Some common allergic reactions are severe breathing, hives, and swelling of lips, face throat, or tongue. Others are confusion, seizures, feeling light-headed, cold skin, severe dizziness or weakness, and slow heartbeats. Contact your doctor immediately you notice these signs.
Usage of Oxymorphone HCL
The drug is indicated for managing severe pain enough to need daily, around the clock, extended period opioid treatment. The drug is shown as an as-needed analgesic.
Due to risks of abuse, addiction and misuse associated with opioids OPANA ER is reserved for patients who immediate-release opioids, or non-opioids analgesics are ineffective
Dosage and administration
Only healthcare professionals skilled in the use of potent opioids in chronic pain management should prescribe OPANA ER. Each dosing regimen for every patient should be initiated individually, considering each patient past analgesic treatment and factor in addiction, misuse and addiction risks. A doctor should monitor patients closely for respiratory depression especially in the last 24-72 hours of taking the drug.
Patients should take the OPANA ER tablets whole, one at a time, with much water to ensure full swallowing immediately after placing the pill in the mouth. One should never chew, crush or dissolve OPANA ER tablets since it will cause an uncontrolled delivery of oxymorphone that can result in death. Patients should administer OPANA ER tablets at a frequency of two times daily. It should be on an empty stomach at least an hour or two after eating.
First timers should administer 5mg OPANA ER tablets orally every 12 hours. This applies to non-tolerant patients too. Tolerant patients can receive at least 60 mg per day. Using higher starting doses if you are not opioid tolerant can be fatal and cause respiratory depression.
Using higher starting doses in patients who are not opioid tolerant may cause fatal respiratory depression. Patients should discontinue all the other opioid drugs when they initiate OPANA ER therapy. Discontinue all other around-the-clock opiate drugs when is commenced. OPANA ER should be discontinued gradually due to its physical withdrawal symptoms.
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